Skin Diseases In Need Of More Awareness

In the basal cell carcinoma, this is the most common skin cancer which is also known as non-melanoma. At the initial stage, it appears as the small lump only on those areas which are specially exposed to the air as well as to the sun. This type of skin cancer is easily recognized and mostly affected the areas like hands, neck and head. It rarely spreads on the other body parts and it also has high cure rate.

Those who are having light colored skin or light eyes are mainly prone to this type of cancer. On the other hand, people with dark skinned are less prone to basal cell carcinoma. The squamous cell carcinoma is quite similar to the basal form of cancer. Symptoms of this cancer are generally present on the ears, lips or even on the whole face. It is easily curable just by following the proper medical treatment. In the initial stages, skin appears reddish and scaly. On the other hand, malignant melanoma is rarer form but still most dangerous of in all other types of skin cancer. Infection of this disease can rapidly spread on the other body parts via lymph nodes and blood streams, people with red or blonde hair or with freckles and blue eyes are more at risk.

Shingles is the most painful disease which appears on the skin in the form of rushes with fluid blisters. Due to the Herpes virus, this disease is caused. The Shingles symptoms are varying according to the different stages. Like, in the first stage, patients may feel normal viral infections, rashes, nausea, headache, fever etc. In the next eruptive stage, patients are suffering with blisters which are appear on the different body parts such as arms, legs, face, buttock and so on. The list of Shingles symptoms, tingling and burning sensation, numbness, and itching, burning pain are also included. In the initial stage, this disease can be easily curable.

Home remedies cold sores are still preferable in most of the traditional treatments. To follow this treatment, you don't need to visit any doctor. There are huge numbers of home remedies cold source which includes taking vitamins and its supplements, diet changes, applying certain type of powder or juice to a sore etc. These remedies will definitely give much relief and it is the best treatment to cure cold sore. Some patients are rubbing or pressing ice cubes on the sore or simply holding cubes against it. As soon as you realize the symptoms of cold sore, you can begin with these home remedies. Holding ice on the sore is the best way to cure and it is considered as the best known home remedy. In the list of other home remedies cold sores include rubbing extract of lemon balm, aloe Vera, tea tags etc. It helps to smaller their size as well as it effectively reduce pain.

Healthyskinguide.net provides proper health guide on the barriers of healthy skins, Types of skin cancer, Shingles symptoms and Home remedies for cold sores.

Automated Random-Access Immunoassay Systems

Automated random-access immunoassay systems are specifically designed to efficiently carry out the advanced analytical requirements of contemporary clinical laboratories and hospital facilities. These systems ensure stable performance and superior accuracy.

High-end Models from Well-known Manufacturers

Automated random-access immunoassay systems are used to perform tests for thyroid hormones, infectious diseases, bone metabolism, reproductive hormones, anemia, assays for cancer markers, allergy, therapeutic drug monitoring, cardiac analysis, tumor markers and other additional assays. High-end models of automated immunoassay systems, integrated with random-access capabilities, are available from well-known manufacturers including Tosoh Bioscience, J&J and Siemens Medical Solutions Diagnostics. Major models offered include Tosoh 360, ADVIA Centaur, Tosoh 600 II, J & J Vitros ECI and Immulite 2500.

Online Shops for Easy Purchase

To purchase the model of automated random-access immunoassay system that suits your research needs, it is essential to approach established suppliers as they ensure branded products, competitive prices, dedicated customer support and proper service contracts. A web search would help you get the necessary information. Most dealers offer online shopping facilities and attractive prices.

Immunoassay System with Extensive Features

The important advantage of automated random-access immunoassay systems are that they offer flexible operation, precision for successful workload management and optimal productivity. Further, these analyzers are simple and easy-to-use, and enable researchers to obtain accurate diagnostic results within a short time.

The various models of immunoassay analyzers come with advanced capabilities to facilitate efficient performance of research tasks. The core features of the Tosoh 600 II analyzer model include:

• Primary tube sampling
• Dual clot detection
• Random access for both routine and STAT immunoassays
• Automated sample dilution and pretreatment
• Throughput of 60 results per hour
• Unit dose test cup reagent system
• First result in ~18 minutes (ST Assays)
• Full test menu
• Third generation sensitivity
• Compact size - less than three feet of counter space

Some models come with high resolution touch screen for trouble-free interaction, automatic reflex testing with cascade options, as well as automated monitoring and maintenance. The devices also feature high on-board refrigeration capacity for reagents and supplies, on-board dilution and automatic repeat capabilities. A major advantage is that automated random-access immunoassay systems require minimal maintenance.

Block Scientific is the affordable source of fine Medical Laboratory Equipments like Centrifuges, Chemistry Analyzers, Immunoassay Analyzers, Blood Gas Analyzers and more.

3 Questions to Ask Yourself When Selecting Quality Medical Supplies

Quality medical supplies are found at the heart of every medical operation you can think of, from big hospitals all the way down to small community clinics. When looked at in another way, you could easily say that these will be the biggest expense that any medical operation has, short of personnel.

Just because it's the biggest expensive doesn't mean that there aren't ways to lower your expenses, or ways to focus on getting the best medical supplies possible. If you've been tasked to handle the ordering of medical supplies, there are just three questions that you will need to ask yourself while you go to select quality medical products.

Naturally, this guide assumes that you will be ordering your medical supplies through the Internet, as going online is the best way to get the deepest discounts and the widest selection. While it's true that there are other sources available, like going into town, the last thing that any busy medical professional should have to do is fight traffic!

Going back to the actual questions, the first thing you should ask yourself is what manufacturer you really want to go with. After all, the last thing that you want to do is select a manufacturer that will not serve your needs well. It's better to pick one or two manufacturers that consistently produce great products than just settle for the one that does a halfway job on the products that they do offer. Your organization's patients deserve the best of care, and that does start with quality medical equipment.

From there, you will need to ask yourself how much you are trying to order at one time. The biggest mistake that many people make at this stage is that they assume they will save the most money by ordering small packages at once, but that's not the case at all. It's better to wait until you have the funds for a very large order, since you will qualify for bulk pricing. It's better to go with bulk pricing since it offers the deepest discounts, which will in turn make it easier for you to order even more equipment as you need it. Some items will not be ordered as frequently, and that's okay -- that will be offset by the everyday run of the mill items that seem to always need ordering.

The final question that you need to ask yourself when selecting quality medical products is how often you want to order them to begin with. Indeed, your initial purchase order is just that -- the beginning of a long line of purchases. By developing a schedule from the beginning, you will be able to eliminate a lot of the hassle and worry of running out of supplies and other stresses that can come about as a result of bad planning.

Overall, these are just guiding questions to get you started -- if you take the tips here to heart, you will have no problem getting quality medical supplies that make the grade each and every time!

Great medical supplies are only a click away -- order yours today!

What Mouli Cohen Has to Say About Biotech Drugs and Innovation

The FTC (Federal Trade Commission), in a recent report, proposed that the 12-14 years that are currently being allotted as a period exclusively for the innovation of products in biotech companies is much longer than required for the purpose.

The report also showed that the development of the generic biotech drugs could be a boon to the health care cost in the U.S. These drugs cost about 10-30%lesser than the conventional drugs in the market today.

The U.S. President, Obama, after the publication of the report, included in his talk to the AMA, the American Medical Association, that the introduction of generic biotech drugs could save the country enormous money. But no one knows how much that money will be and how fast it will be earned.

It is definite that the introduction of generic biotech drugs will be a boon to the economy but this boon is not quantifiable. Also, the biotech sector will undergo some changes that will be immeasurable according to the industry insiders.

According to Mouli Cohen, investor, entrepreneur, philanthropist and the founder of the Voltage Capital is of the view that this proposal shall make innovation less attractive. He believes that innovation and the capability of driving processes towards outcome that are quantifiable is what business is all about. And killing this process can reduce them to just mediocre players. He says that innovation is needed to run a business and there is no alternative to that.

PharmaTiles also pointed out the concerns that if generic biotech drugs come hastily into the market, then will biotech companies recoup their R&D investments?

Cohen states that R&D is very expensive and most of the pharmaceutical companies do not bother investing in R&D. The burden is then transferred to the academia and the biotech companies. AT the end of it, someone has to do the sponsoring. The costs will keep shifting but if any compensation is made and that turns out to be unfavorable, then the entire medical industry will suffer largely. This implies that the biotech sector will suffer some major problems in funding for R&D in the coming five years.

About two thirds of the funds go to the small biotech companies that earn no profits and which heavily rely on private investment.

If the proposal is implanted, then the impact of innovation will be greatly minimized. With these new regulations, the industry is going be subjected to rapid change though the new ideas and the products shall still be as solid as they were. Cohen suggests that care should be taken and consequences should be weighed before any action is taken.

Mike Casnet has been writing articles for 3 years. He like to write business, travel and health articles for different people. He is now developing his own webpage for clients who wants to try his service like Mouli Cohen

Save Money on Your Prescriptions With a Simple, Little Know Pharmaceutical Trick!

For the sake of a case study let's consider you are currently taking Lipitor at a 10 mg per day dosage.

If you purchase Lipitor from Walmart, it will cost you apx. $100.00 per month x 12 months = $1200.00 per year.

Now let's take a look at the cost of that same medication, Lipitor, by simply splitting the pill dosage in half.

Purchase the same pill in 20 mg for Walmart at a cost of $143.00 for 30 tabs x 6 months=$858.00

Now you will only have to purchase the 20 mg. tabs every other month because you will be splitting the dosage in half. Your savings per year would be 342.00 per year.

Same medication, same dosage but greater savings.

Now lets' say you do a little price shopping on Medical Price Point's comparison site.

Right now the cheapest Lipitor we could find is at Target. The cost from their Pharmacy is $98.00 for 30 tabs of 20 mg Lipitor. Multiple that times the 6 months = $564.00 Compared to the 10mg price of $1200.00 per year, you would save a grand total of $636.00

Not bad for just educating yourself on a little known Pharmaceutical trick. You need to remember however, that time released capsules are not splittable and this method will only work with "pills".

Here are a couple more examples;

Sertaline (generic Zoloft) 50 mg pills at Costco x 12 months= $35 x 12= $420/year

Sertraline (generic Zoloft) 100 mg pill at Kmart x 6 months= $5 x 6= $30/year

$420- $30= $390 per year savings

Amlodipine (generic Norvasc) 5 mg pills at Walmart x 12 months= $40 x 12= $480/year

Amlodipine (generic Norvasc) 10 mg pills at Kmart x 6 months= $5 x 6= $30/year

$480 - $30= $450/per year savings

Please take a few minutes and join the community at Medical Price Point, it's Free. Telling others about your medical savings tricks or reading about others will help us build a community of Smarter Medical Shoppers.

Charles Bagley started Medical Price Point for the specific purpose of educating the public on Medical Pricing in the United States. We have compiled pricing from every Medical Field to be used for Free to help the greater public, "nudge" Health Care providers into making pricing more transparent. MedicalPricePoint.com offers a free online community forum to help build a pricing database for all to see and use. Join Medical Price Point's growing community of Member involvement. Get involved, Get educated, Save money!

http://medicalpricepoint.com

Growing Fame of Pharmaceutical Engineering in Various Sectors

Pharmaceutical engineering is a branch of chemical engineering that has a wide range of applications in numerous sectors. It has contributed a lot to medical science by developing medicines for many fatal diseases. These medicines have the potential to fight the deadliest and life-taking diseases. It is a combination of biology, chemistry, physics and biochemistry. It uses the concepts of all these branches to develop effective medicines.

Pharmaceutical engineers have huge job opportunities where they can show their proficiency. Various drug designing centers, pharmaceutical industries, biomedical industries, R&D labs and other sectors are inviting young and dynamic talents to join them and become a pat of their organization. They can practically implement the subjects they have studied under their course. Because of newly emergence of Pharmaceutical Engineering and large requirements of working personnel in biomedical industry and other sectors, graduates are taken into contemplation.

Pharmaceutical engineers must be updated with latest ideas and techniques as they have to develop remedies for those diseases whose solutions are not present till now. They have o discover future medicines also. Their skills and knowledge in numerous subjects can provide them job opportunities in various sectors like nanotechnology, cosmetic, biomedical, nutrition and other work fields. All these are some of the emerging technologies that determine the scope of pharmaceutical engineering. Professionals are highly demanded in numerous fields where they can prove their worth. Hence we can say this branch of science has created wonders in various sectors. The future of this stream is very bright and its success is never ending.

For more information on Pharmaceutical engineering and the benefits of Pharmaceutical engineering please visit the mentioned website

Community-Associated Bacterial Infections on the Rise

For years, health researchers have warned the public of the growing danger of antibiotic-resistant strains of bacteria whose growth is spurred on by the overuse of antibiotic drugs. Doctors often supply antibiotic medication to patients who mistakenly believe that the drugs will help them with a given illness which, in fact, is not treatable with antibiotics (such as viral infections). Some studies indicate that doctors may over-prescribe to avoid conflicts with patients who expect antibiotic treatment for respiratory tract infections (often associated with the common cold virus), despite the fact that only 1 in 4 of those patients actually desires such a treatment.

As the superbug MRSA (short for methicillin-resistant Staphylococcus aureus), a colonizing bacterium which is highly resistant to antibiotics, makes its way into more and more hospitals and other community facilities, the concern over a possible public health epidemic is growing. Between 1999 and 2006, a sevenfold increase in MRSA-related infections was found in outpatient hospital wards.

Today, additional studies indicate that not only are mortality rates and lengths of hospital stays not getting any better, but hospital-associated infections are actually on the rise, accounting for about half of all infection deaths among hospital patients. Previous research has established a link between the two, but the latest reports from scientists studying the phenomenon provide conclusive evidence that community-associated strains are actually the root of many of the infections. The Center for Disease Control reports that about 1.7 million hospital infections occur each year, with 99,000 associated fatalities.

Sepsis, pneumonia, and other infections resulting from exposure to community-associated bacteria could all be reduced by implementing additional measures of safety in hospital wards to reduce the spread of the illnesses, but funding for those measures can be difficult for doctors to justify to administrators. As one doctor notes, "Even when physicians are gung-ho to do something about infection control, they may not have buy-in from hospital administrators. They may still ask, 'Why do you need $500,000 if it isn't going to do anything for the bottom line?'"

The government is beginning to crack down on hospital-related infections by denying payment from Medicaid or Medicare for costs resulting from avoidable complications. Unfortunately, that may not do much good - documentation of such infections isn't easy to track, making the rule harder to enforce. Worse, hospitals could simply avoid such penalties by intentionally misclassifying infections to prevent government programs from denying payout.

In the meantime, the best rule of thumb for antibiotic use is still to try not to use them. If you visit a doctor about an illness, listen carefully to what he or she has to say about the likely cause of your illness. Often a simple blood test can determine if the condition is caused by a virus or a microbe - and remember that antibiotics won't help fight off a virus one bit. If you are prescribed an antibiotic, ask your doctor why it is necessary and what his basis for the prescription is. If the answer amounts to "just in case", you may want to seek a second opinion.

Randy McIntire is a technical writer specializing in mobility devices for seniors and the disabled. Randy's particular area of expertise is lift chairs. For more information about lift chairs, visit US Medical Supplies.

Tips to Easily Swallow a Pill

Some people may find difficulty to swallow pill, especially if the pill is too big for your throat. However, if you are considering your illness, you have to be able to swallow your pill for medication or you will not recover. At this time, this article will provide you some tips that will help you to easily swallow a pill for your medication.

When you find that the pill is too big to be swallowed, you need a pill cutter to cut it into smaller portions. When it is smaller, it will be easier to go down to your throat. In the process of swallowing it, you need to tilt your head back down and tuck in your chin.

Moreover, by using water, you will be easier to swallow the pill as well. In this process, you have to make sure that you are in standing up position or sitting up position. It is because when you are swallowing while lying; it is potential for you to get your throat gagging. Besides, you can also use carbonated beverage because it can also help you to be easier in swallowing the pill.

The other way to easily swallow a pill is by using soft food like puddings, applesauce, or yogurts. In this process, you need to make sure that the pill will work with the food. Also, you need to check on the warning of any interaction, especially for dairy products. Do not use too much food while you are swallowing the pill. Just use enough portion of food to swallow it.

If these all techniques to swallow pill cannot work, you need to talk to your doctor and ask for liquid medication instead of the pill. And for those who have already succeed to swallow pills for medication, there is a medical equipment called electronic pill dispenser that will help you to remember in taking your medication as needed, on an hourly or daily basis.

Ins and Outs of Cold Sore Treatments

Cold sores (or fever blisters) are itchy, painful and unsightly -3 out of 10 people get them on a regular basis but nobody talks about them!

Cold sores are caused by the herpes virus.

There are two kinds of herpes infection -HSV1 which most often causes cold sores on the lips; HSV2 usually causes infection in the genital area and is considered a sexually transmitted disease (STD).

Note: Cold sores (HSV1) can be spread to the genital area and genital herpes (HSV2) can be spread to the mouth.

You can get the infection from kissing someone with the virus or eating/drinking after someone who is infected. Many parents pass the virus to their children. Once you have the infection, you can not be healed -but you can prevent and treat cold sores.

Cold sores (fever blisters) usually start as a small sore on the lip which slowly grows larger and looks like a blister. The "blisters" will break open and eventually scab over and fall off. During this time, you can pass the virus to others and spread it to other areas of the lip and body.

The good news is that they will usually clear up within a few days to two weeks.

The bad news is that they can be painful, unattractive and can take TWO weeks to clear up!

You should start treatment as soon as you know a cold sore is coming (either from itchy/tingling feeling or seeing the small sore).

To treat cold sores:

1. Apply ice for a 3 minutes 4 times an hour for 2 hours.

2. Start taking Motrin (ibuprofen) - 1 to 2 tablets every 4 to 6 hours or Tylenol Extra Strength (acetaminophen) - 1 tablet every 4 hours.

3. Avoid acidic foods (pizza, orange juice) -you'll know it is bad because it will most likely HURT.

4. Rinse with warm water mixed with 1 teaspoon of baking soda

5. Apply Abreva cream (available OTC at the pharmacy) -apply 5 times a day for up to 10 days. Abreva is the only OTC medication proven to decrease symptoms and aids in healing.

6. If the cold sore is painful -apply Anbesol or Orajel over the Abreva to help numb the area.

7. Take a prescription drug like acyclovir or Valtrex. These meds are by prescription only, so talk to your physician about them. The recommended doses are...

* Valtrex (valacyclovir) - Take 2 Valtrex 1,000 mg tablets twice daily for day 1 then take 1 Valtrex 1,000mg tablet twice a day on day 2.

* Zovirax (acyclovir) -Take acyclovir 400mg tablet five times a day

* Both medications work -Valtrex is taken less often and may be more convenient but acyclovir comes in a generic and can be less expensive.

8. You can also use some natural supplements:

* Lysine -500mg to 1,000mg/day for 5 to 10 days

* Vitamin C -100 to 500mg/day for 5 to 10 days

* Lemon balm -apply 2 to 4 times a day for 5 days

To prevent future outbreaks of cold sores:

1. Stress, sun and illness can lead to an outbreak of cold sores -so avoid when at all possible!

2. Avoid drinking after, using utensils or kissing anyone with an active infection

3. Prescription drugs...

* Zovirax (acyclovir) -Take 200mg three to five times daily

* Valtrex (valacyclovir) - Take 500mg one time daily

So, now you know...and knowing is half the battle!

Nova Simpson, Pharm.D.

http://www.getpharmacyadvice.com

My best bud -Cate Sibley, Pharm.D. and I started our own pharmacy blog -where you can ask any questions any time!

Want to learn about genital herpes?

http://www.getpharmacyadvice.com/genital-herpes-and-you/

Stem Cells and Regenerative Therapies - How to Extract the Essence

The process of finding and developing new drugs is long and costly. It takes years and millions of dollars for one single new drug to be developed from the stage in which a candidate molecule was identified to the ultimate stage of regulatory approval for marketing. The new era of stem cells and regenerative medicine does not shorten this process. On the contrary, it presents new challenges in the road through translation into approved therapy. The challenges are due to the completely new and different structure of the final product. Patients are treated with living cells instead of active molecules. The road to develop new cell based therapy is not less long, complicated or costly than the road to develop conventional drugs.

The amount of information in the media, both professional and popular, is huge. Nonetheless, most of it, although interesting and supportive for further development, is not applicable for present patient's needs. If we want to evaluate the current potential of a new therapy, the most important parameter is how close it is to clinical utilization. Practically, we want to know if the therapy is used already to treat diseases in human beings. Such treatment can be either experimental in its early stages, or ultimately, approved by regulatory authorities and provided by companies, clinics and hospitals.

Let us look at the various stages of development and thus be able to identify the most relevant ones according to this simple principle. Research is conducted on the molecular and cellular levels, as well as in experimental animal models. Such research generates large amount of data, and set the basis for identifying new modules of therapies. Once a promising candidate is identified, the process of drug or cell based therapy starts. It needs full characterization, understanding mechanism of activity, optimization of large scale production, thorough analysis of safety profile, establishing quality control tests and more. The first stage is a general or theoretical research, while the second is called pre-clinical development. Once this stage is accomplished, the product is ready for clinical studies, following the submission and approval by regulatory body. This third stage is termed clinical development. The clinical studies are conducted at three stages and if successful, approval for marketing is obtained. A product or process which is presently being tested in clinical studies, can be better evaluated for its current application. Being in the clinical stage of development is meaningful for practical purposes, although only few products will turn to be safe and effective, and approved for clinical use. The clinical phase of the development may take about 2 to 5 years, and sometimes longer.

In some countries, it is legal and possible to offer cell based treatments even before the full scale clinical studies were completed. Clinics and hospitals in such countries are treating patients for life threatening and chronic diseases before thorough testing and approval by regulatory agencies in the US, Europe or other countries. Most of these clinics do not conduct or publish systematic clinical trials, but they usually provide information on the technologies and therapeutic approaches used. Can this be regarded as "tested in human patients"? The answer is no, but it is up to the patient to decide whether he would like to take the risk with all its implications, rather than wait for the therapy to be approved.

Most reliable information on ongoing clinical studies is found in the FDA (US Food and Drug Administration) database - Clinicaltrials.gov. Although US based, most clinical studies from many other countries as well are published in this comprehensive website which also includes effective internal search option. However, early pilot and phase I studies are usually not listed there. Results on clinical studies can be found in the well known scientific literature data base website, the US NIH (National Institute of Health) PubMed -Ncbi.nlm.nih.gov. Here again, the relevant clinical data will be difficult to extract from the plethora of scientific information, and it is mostly used by professional scientists. Large medical centers will also provide updated information on scientific achievements, along with clinical trials and results. Many other blogs and websites, as well as professional organizations, provide information on stem and cell therapy news. For clinical relevant information on cell therapies - My New Therapy website is patient oriented and focuses on clinical data. As suggested, you can evaluate the current clinical relevance of a piece of news according to its proximity to being tested in human patients, or preferably, if being already a part of reliable clinical study. This rule of thumb, being tested in human patients, can help to better judge for practical purposes or needs, the clinical value of a product, service, technology or process.

Dr. Avi Treves is currently the Deputy Director of the Sheba Cancer Research Center at the Sheba Medical Center in Israel. Operating the Ella Institute for treatment and research of Melanoma, the Family Cord Blood Bank and Bio Regenerate Inc, a start up company developing adult stem cells technologies and storage services.

Previously, the founder and CEO of Gamida Cell Ltd.; CEO of Hadasit Ltd., the tech transfer company of the Hadassah Medical Center.

PhD from the Weizmann Institute of Science, Rehovot, Israel; Post doc at Stanford University Medical School, CA USA.

Expert in developing cell based technologies, products and their clinical applications. Adviser and scientific board member for biotech companies. Co-author of more than 90 scientific publications and 10 patents.

For more information on clinically relevant stem cells, regenerative medicine and immunotherapy go to: http://www.mynewtherapy.com

Pharmaceutical Development As a Means For Ensuring Financial Success

Developing a new pharmaceutical active ingredient isn't just about developing a molecule with the best biological activity. The physical form has to be optimised to ensure the top possible performance and that no one can find a superior form and usurp your hard won patent position.

Pharmaceutical development is the progression of a new chemical entity found in early screening through to the later stages of clinical development. Pharmaceutical development includes the construction of a scaleable manufacturing process as well as refinement of the optimum physical form of the Active Pharmaceutical Ingredient (API).

Pharmaceutical development starts with an active compound that displays the desired response in an assay. However, in vivo (in the organism), the compound might not get to the point of action as it so easily did in vitro (lit. in glass). Pharmaceutical development is needed to turn the compound into a form that is stable, is biologically available and can be made into the most favourable formulation. A balance is needed between the water solubility and lipophilicity (ability to dissolve in fats) characteristics of the drug. Skilled scientists will be able to turn a compound with poor physical properties into one that can be crystallised and processed effectively. A Salt screen will lead to candidate compounds that can subsequently be selected and further optimised. A balance will need to be made between optimal drug performance and manufacturability.

It is essential to integrate manufacturing expertise with solid-state expertise using a diverse range of state-of-the-art equipment and facilities operating to current Good Manufacturing standards. Scale up and production of kilo quantities of the drug under GMP conditions completes the early pharmaceutical development phase. If properly conducted, the optimal physical form will be taken forward coupled with the means to manufacture. Ultimately your intellectual property will be secured and long term financial success guaranteed.

Static Dosing and Rhythmic Cycling

If your physician feels you are an ideal candidate for static dosing of bioidentical hormones, he or she will initially prescribe a low dosage of the hormones to test your body's response. Following several months of taking bioidenticals at a low dosage, doctors will then reorder blood samples, which will be scrutinized for your detailed hormonal levels. If your symptoms are somewhat alleviated and the levels remain relatively optimal, doctors will the set forth a regimen of taking bioidenticals on a daily basis, with an increase in dosage on the eighteenth and twenty-eighth day. The increase in dosage on these two days will mimic the natural physiology of a young woman's body, induce a period, and give a woman the full complement of hormonal attributes they enjoyed before the aging process.

The second method of taking in bio identical hormones for women involves charting and taking the hormones on a rhythmic cycle in concurrence with the lunar phases and tides. This process, although seemingly a little too out there for some women, really makes sense and attempts to mimic the reproductive and hormone cycles of women prior to the advent of modern society, and all the associated stress, irregular sleeping patterns, and in turn, irregular hormonal production levels. One of the more well-known processes of administering bioidenticals rhythmically is known as the Wiley Protocol, which advocates large dosing of hormones, natural and safe bioidentical hormones, to women in tailored ratios for their unique bodies. Many women have found a large amount of relief and overall happiness in the health and their lives while using rhythmic cycling and the Wiley Protocol

Every woman wants to take care of their body, for as long as possible. In many women cases today, the option to utilize hormonal replacement therapy is a wise and healthy decision, if made with the intention of using bioidentical hormones. The numerous side-affects, such as breast and ovarian cancer, associated with synthetic hormones, not to mention the lack of benefits in light of bioidentical hormone replacement therapy's offerings should truly be the deciding factor for any woman serious about living a long, healthy, happy lifestyle.

Human growth hormone decreases as we grow. With additional Testosterone Therapy, natural growth hormone production can be increased and the side effect of aging can be slowed, leading to a more productive lifestyle please visit our website.

Tips to Ordering From an Online Pharmacy

Do a fast search of online pharmaceuticals on Google and you will be spoiled with choices. In truth, a little of these drug stores are trusted and will execute quality services. How does a person execute sensible purchasing by analyzing every online pharmacy site? Here are a few advises you can follow in guaranteeing one of a smart medicine purchase.

The first point you must look for is an comprehensive web pharmaceutical. The most reliable pharmacy pages are able to comprehensively inform visitors regarding their stock, pricing, and reduced rate offers. They should be direct about telling people these features. If the prices and brands appear inaccurate and vague, do not trouble yourself ordering from the website. Reliable websites also have comprehensive information on the recent medicine research and helpful tips on buying medicine online.

Apart from analyzing the clarity of the pricing, you should also evaluate how the costs vary among the online pharmacy sites. Obviously, there will be a difference between companies that sell the same medicines. Don't endanger your well being by being cheap and opting for the lowest price. You may end up wasting your cash on an ineffective fake medicine.

Always do your homework on the online pharmacy you're considering. This is very crucial for small businesses in the market. Should they have a phone line on the site, call it and ask them questions that can clarify your queries. Visit pharmacy review websites and message boards to read actual opinions from then and present customers. Research on the way the pharmaceutical delivers their products. If a lot of customers complain of damaged deliveries, then it is best to keep away from that pharmacy. It also helps to talk to your friends, coworkers, or family members if they've experienced purchasing from a well known online pharmacy site.

Aside from checking out references, you must also visit the website for a number of weeks. If they don't renew the website for several weeks, then it must be scam. The website should also have an easy-to-navigate layout. Apply your common sense to check if the webpage has a simple and pleasing display. Instant cash scam sites won't put as much effort into their site's look and features.

Personal health is the original priority in purchasing medicines, so always consult your doctor before buying. Aside from receiving the necessary note from them, they may be able to provide you some reliable online pharmacy sites. You will not have to be anxious about getting scammed off your cash if the site recommendation comes from your doctor.

You also need to study the buying process of the online pharmacy. Ensure that the site shows you the data form for the encryption they use, specifically when they ask for your bank account or credit card information. Knowing they use the encryption guarantees you that the info sent ]is safe.

The most trusted sites always request for a prescribed note for your medicine purchase. Make sure you understand how you will send the said prescription to the online pharmacy. The prescription note is usually copied then delivered through email or a duplicate is faxed. Send an email to the company to clarify the process and see if you will have to talk to them to confirm your order.

The online pharmacy must have a very accessible customer service number. If the company is direct about instructions and quickly verify your purchase, you won't have to call their hotline. However, in case of sudden situations, it always helps to know you can quickly talk to them.

Trusted online companies are very understandable regarding their return policy. They should assure you that they will give back your money if you receive a wrong order. If they require non-traceable pay means, you will end up having your money stolen in lieu of being properly spent. There are many web pharmacies online to choose from. Ordering the right one is a matter of common sense and practicality.

See 4RX Review including neutral remarks concerning Online Pharmacies.

Design Theory of Closed System Drug Transfer Devices

Recent surveys have shown that traditional vial-to-syringe technique is one of the riskiest modes of occupational exposure to hazardous drugs. Vial over-pressurization can lead to spraying and leakage. These sprays and spills are frequently unnoticed, which may result in exposure of contaminated finished products to staff and patients in healthcare centers.

Closed System Drug Transfer Devices are special protective devices, designed to reduce the risk of occupational exposure. They provide a safer system for administrators to reconstitute and transfer hazardous drugs from manufacturers drug container to the patient specific equipment while operating patients. These have closed cabinets which prevent spills, leakages during the preparation, administration and disposal of these drugs.

Various types of drug transfer devices have already entered into the market and have made success in delivering effective results. They include a complete line of closed, vial and bag access products for safe preparation, transfer and administration of hazardous substances. They also assure protection through the entire spectrum of hazardous drug delivery.

Genie, designed by ICU Medical System is a closed, needle-free, vial-access device that automatically equalizes vial pressure. When the desired amount of drug is taken out from vial, the genie balloon automatically inflate to equalize the pressure thereby reducing aerosols, vapors and leaks caused by pressurization of vials. Similar systems having dual-venting feature to enhance the equalization of vial pressure and automatically self-seals when disconnected, have been already designed.

There are various guidelines on the effective way of usage of these devices, which must be followed by nurses and practioners in healthcare centers. These devices should always be used with in a ventilated cabinet while following appropriate personal protective equipment and work practices. Staff members should be properly instructed and observed regularly while using these devices. In addition, system failure reports should be immediately reported by all users including pharmacy and nursing, to the manufacturer.

Presently, use of Closed System Drug Transfer Devices has been the strategy employed by healthcare centers, to minimize the risk of exposure to hazardous drugs. However, the consistent and proper usage of these systems is paramount in ensuring containment.

For more information on Hazardous Drugs and the benefits of Exposure to Hazardous drugs please visit the mentioned website.

Regenerative Medicine - Treatment With Induced Pluripotent Stem Cells

New developments in the use of induced pluripotent stem cells (iPS cells) are appearing every month in the literature. The initial hurdle is to be able to reprogram adult human cells without using agents that might cause cancer. The first reprogramming method used a viral delivery system to introduce the reprogramming genes into cells. But a virus can insert into the cell's genome, possibly causing severe unanticipated outcomes such as cancer.

Also, refinement of the reprogramming factors is necessary. The initial group was composed of Oct-4, c-Myc, Sox2, and Klf4 genes. c-Myc has potent oncogenic properties - expression of c-Myc can cause a cell to become cancerous. c-Myc was discovered in the late 1970s - expression of c-Myc has a profound role in the development of breast cancer and has a central role in most types of human malignancies.

In order for these cells to be used safely in humans, reprogramming alternatives to c-Myc needed to be identified. An optimal scenario would be to identify alternatives to using any gene for reprogramming. Inserting new genes into a cell could result in mutations, disruption of other normal genetic processes, and additional negative effects. Such deleterious outcomes would increase in number and severity as cells and tissues introduced into a patient continue to divide and replicate.

The field is moving forward quickly. Many research teams have been successfully investigating the use of small molecules as reprogramming factors. Small molecules include very short nucleotide segments (nucleotides comprise the basis of the genetic code), peptides (amino acid sequences), and short-chain sugars. Recently a team led by Dr. Hongyan Zhou at the Scripps Research Institute in La Jolla, CA, generated induced pluripotent stem cells using direct delivery of a set of reprogramming small molecules. This groundbreaking work provides a new method of creating safer cells for potential uses in treatment and transplantation.

Initial work is being done to use iPS cells for the treatment of many serious and life-threatening diseases. Important preliminary work has been done with amyotrophic lateral sclerosis (ALS), Parkinson's disease, sickle cell anemia, thalassemia, muscular dystrophy, and diabetes.

For example, researchers have been able to generate large numbers of iPS cells from skin cells taken from an 82-year-old woman diagnosed with ALS. These cells could be directed to become motor neurons, which could be used to replace diseased nerve cells in a patient's spinal cord. This research proves that sufficient induced pluripotent cells can be produced from cells taken from an elderly patient. iPS cells might be used to develop treatments for other diseases which specifically affect the aged.

Sickle cell anemia has been reversed in mice using induced pluripotent stem cells derived from their own cells. Somatic cells were obtained from humanized sickle cell anemia mouse models. The cells were reprogrammed to iPS cells. The genetic defect was corrected in the pluripotent cells which were then differentiated into blood cell precursors. These normal blood-forming cells were then transplanted into the original mice, who subsequently recovered from sickle cell anemia.

This successful proof-of-concept in humanized sickle cell anemia mice points the way toward using iPS cells in the treatment of a wide variety of deadly diseases.

David Lemberg, M.S. in Bioethics, Albany Medical College, May 2010. Consultant, Author, Speaker. Research interests - health care and health care policy, reproductive technologies, genetics and genomics, K-12 science education Executive Producer, SCIENCE AND SOCIETY, http://scienceandsociety.net. Twitter - http://twitter.com/david_lemberg. Visit SCIENCE AND SOCIETY for cutting-edge interviews with Nobel Laureates, trendsetting industry executives, and best-selling authors in the fields of cancer research, genetics, health care policy, nanotechnology, and space exploration.